The show will, once again, be a pre-recorded video presentation available to watch online.
As in previous years, Nintendo will follow its big announcement broadcast with three days of live streaming via Nintendo Treehouse: Live - which promises Nintendo Switch gameplay with developers, starting with a deeper dive into Smash Bros.
E3 will also see the Splatoon 2 World Championship semi-finals (Monday 11th June, 11.30pm UK time), finals (Tuesday 12th, timing TBA) and a Smash Bros. Invitational tournament where fans play the new Switch game.
Nintendo Switch - Neon Red/Neon Blue
£279.99 Buy Now at Amazon
So, what else do we expect to see from Nintendo at E3? Well, the upcoming Pokmon game for Nintendo Switch seems a safe bet - we Kanto wait to see it. It will also be a year since Nintendo first announced Metroid Prime 4 - and while it may not be released in 2018, E3 feels the right moment we get an update. How about a Metroid Prime Trilogy port to keep fans tied over, too?
We'll be at E3 reporting all the announcements live.